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The University of Wisconsin

Program in Virology

Pre- and post-doctoral
opportunities in Virology

Description of the program:

The Program in Virology at the University of Wisconsin-Madison is an interdepartmental program composed of faculty from 15 different departments. Areas of research include the molecular biology and genetics of viral transcription and replication, virus structure and function, viral pathogenesis and oncogenesis, host response to virus infections, and antiviral therapy. A Ph.D.degree is offered. It is designed to provide broad training in procaryotic and eucaryotic molecular biology with an emphasis on the use of viruses in defining basic concepts in biology and the understanding of their role in disease.Post-doctoral opportunites exist in most of the laboratories. All applicants accepted into the Program receive competitive financial support.


Paul Ahlquist RNA-dependent replication and transcription of bromoviruses; RNA virus recombination and host specificity.
Curtis Brandt Genetics of herpes simplex virus virulence in ocular disease; viral immunology and antiviral therapy.
Benjamin Brooks Neurotropic virus infections of blood-brain barrier cells; molecular determinants of agerelated retrovirus and lentivrus restriction in the central nervous system.
Steve Clark Oncogenic transformation of hematopoietic cells by retroviruses.
Theresa Compton Molecular mechanisms of human cytomegalovirus host cell recognition/attachment and virus entry.
Elliot Dick Mechanisms of controlling transmission of rhinoviruses and other respiratory viruses.
William Ershler Influenza virus biology and vaccine development; viral induced immuno- senescence.
John Fleming Immunopathogenesis of viral- induced demyelination by coronaviruses.
Paul Friesen Control of baculovirus replication; baculovirus expression vectors; invertebrate retrotransposons.
Thomas German Structure and function of tomato spotted wilt virus; genetically engineered resistance to plant virus infection.
Robert Goodman Plant defense responses to infection by tobacco mosiac virus and geminiviruses.
Stefan Gravenstein Immune recognition of influenza viruses; epidemiology of influenza.
Virginia Hinshaw Molecular basis of influenza virus pathogenesis; immune recognition of influenza viruses.
Paul Lambert Molecular genetics of papillomaviruses; the role of papillomaviruses in human cancer.
Geoffrey Letchworth Herpesvirus penetration, local immunity and vaccine development; rhabdovirus persistence.
Daniel Loeb Replication of hepatitis B virus; reverse transcription of LINE 1 elements.
Mirek Malkovsky Molecular mechanisms of immunological and non-immunological resistance to primate immuno-deficiency viruses.
Douglas Maxwell Molecular characterization of single stranded DNA plant viruses.
Janet Mertz Control of viral transcription, RNA processing and translation in mammalian cells; SV40 T antigen function.
Max Nibert Reovirus structure and disassembly, early steps in infection, pathogenesis.
Christopher Olsen
Ann Palmenberg Molecular biology of picornaviruses; viral translation, proteolytic processing replication, and evolution.
Antonito Panganiban Molecular biology of HIV and SIV replication and pathogenesis .
C. David Pauza Pathogenesis of primate retroviruses; host and virus gene control of infection; mucosal immunity to retroviruses.
Roland Rueckert Neutralization by antibodies; structure and assembly of picornaviruses and nodaviruses; mechanism of drug resistance in common cold viruses.
Maria Salvato Mechanisms of viral persistence and immunosuppression; molecular biology of arenaviruses.
Kevin Schultz Primate retrovirus infection; molecular biology and pathogenesis of arboviruses.
Ronald Schultz Viral pathogenesis; immune response and viral immunoprophylaxis.
Paul Sondel Lymphocyte interactions with virally transformed and malignant human cells.
Bill Sugden Mechanisms by which herpesviruses immortalize cells; herpesviral latency and re- activation.
Waclaw Szybalski Transcriptional controls and regulatory circuits in bacteriophage lambda.
Russell Tomar Effect of retroviruses on host- immune response; viral pathogenicity.
Thomas Yuill Virology and epidemiology of arthropod-borne viruses; alphaviruses and bunyaviruses.

The Madison campus:

The University of Wisconsin-Madison, established in 1849, is recognized as one of the leading institutions of undergraduate and graduate education in this country. Located along the shores of Lake Mendotain Madison, the capital of Wisconsin, theUniversity, with its enrollment of 40,000students of which 11,000 are graduate students, is a center of cultural activities in this city of 200,000. The University, home of the 1993 Rose Bowl champions, boasts excellent indoor and outdoor recreational facilities available to all members of the academic community. In addition, the natural beauty of Madison, including its five lakes, the university arboreteum, and many parks, invite year-round activity.

Application information:

Applicants to graduate study should haveadequate training in chemistry and in the biological sciences. All applicants are expected to take the Graduate Record Examination including an advanced test in chemistry or biology. Applicants should be submitted by January 15. The Ph.D. Degree in the Program in Virology is administered through the University of Wisconsin Cellular and Molecular Biology Program.Postdoctoral applicants may apply to the program as a whole or are invited to write directly to individual faculty working in theareas of interest to the applicant.

Financial assistance/housing:

Participants in the Program in Virology are supported by research assistantships or research associateships which are available to both foreign and domestic applicants.In addition, predoctoral and postdoctoral traneeships are available to a limited number of program participants each year.These traineeships are available only tocitizens or permanent residents of theUnited States. While most students and postdocs live off-campus in the various neighborhoods of Madison, there is limited, low-cost housing available on campus. A non-campus assistance center provides easy access to housing listings.

Requests for further information should be directed to:

The Program in Virology Cell and Molecular Biology Office Robert Bock Laboratory, rm 413 University of Wisconsin-Madison 1525 Linden Drive Madison, Wisconsin 53706
tel.608-262-3203/ fax. 608-262-4570

CCMV (Data provided by Purdue)

rhinovirus 14 VP1 /drug (WIN52035) interaction

CPV (Data provided by Purdue)

Illustration of AMV showing assymetry of T3 structure

receptor / rhinovirus 14 interaction

Computer images are courtesy of Jean-Yves Sgro,
Molecular Virology Institute, University of Wisconsin.

© 1994-1997 Stephan Spencer & Jean-Yves Sgro. Web Design By Internet Concepts LLC


Last Modified July 01, 1998